Clinical Case Study · 004

Returning to Community Life Through Treatment of Multilevel Vertebrogenic Pain

De-identified · No PHI

Clinical Question

Can careful clinical evaluation identify multilevel vertebrogenic pain in a patient with persistent chronic axial low back pain despite extensive conservative treatment and multilevel degenerative spinal disease?

De-identified sagittal lumbar MRI (T2-weighted) demonstrating multilevel Modic Type 2 endplate changes extending from T12 through S1, with multilevel degenerative disc disease and disc height loss.Show labels Enlarge

Sagittal lumbar MRI. Multilevel Modic Type 2 endplate changes extending from T12 through S1, with multilevel degenerative disc disease and disc height loss, interpreted together with the clinical picture to support multilevel vertebrogenic pain. De-identified · no PHI.

Treated vertebral levels
T12 · L1 · L2 · L3 · L4 · L5 · S1
#Imaging findings
  • 1Modic Type 2 endplate changesUpper levels — T12, L1, L2
  • 2Modic Type 2 endplate changesMid levels — L3, L4
  • 3Modic Type 2 endplate changesLower levels — L5, S1
The Diagnosis

Reading the Imaging

The MRI is interpreted together with the patient's history, examination, and treatment response.

Patient Overview

A 78-year-old woman presented with persistent chronic axial low back pain that had progressively limited her daily activities and quality of life despite extensive conservative treatment.

Previous management included physical therapy, a home exercise program, oral medications, anti-inflammatory medications, oral corticosteroids, epidural steroid injections, facet joint injections, and activity modification. Despite these treatments, she continued to experience function-limiting axial low back pain affecting walking, prolonged standing, movement, bending, and routine daily activities.

Clinical Evaluation

Comprehensive review of the patient's history, physical examination, characteristic pain pattern, and lumbar MRI demonstrated findings consistent with chronic vertebrogenic pain.

Lumbar MRI demonstrated multilevel Modic Type 2 endplate changes extending from T12 through S1, lumbar levoscoliosis centered at L3–L4, multilevel degenerative disc disease, multilevel disc height loss, chronic vertebral endplate remodeling, multilevel facet arthropathy, and multilevel foraminal stenosis.

The Modic endplate changes, interpreted together with the patient's history, physical examination, characteristic pain pattern, and unsuccessful response to prolonged conservative treatment, supported multilevel vertebrogenic pain. A multilevel Basivertebral Nerve Ablation was subsequently performed across the affected vertebral levels, from T12 through S1, utilizing the Stryker OptaBlate® system.

De-identified sagittal lumbar MRI (T2-weighted), an adjacent slice in which the multilevel Modic endplate changes and degenerative disc disease are seen to differing advantage.
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De-identified sagittal lumbar MRI (T2-weighted), an adjacent slice demonstrating the multilevel Modic endplate changes at differing levels than the neighboring slices.
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De-identified sagittal lumbar MRI (T2-weighted), an adjacent slice in which additional levels of the multilevel Modic endplate changes are brought out.
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Additional sagittal views of the lumbar spine from the same MRI study. Across adjacent slices, the multilevel Modic endplate changes and degenerative disc disease are demonstrated to differing advantage from the low thoracic spine through the sacrum. De-identified · no PHI.
The Procedure

Fluoroscopic Images of Radiofrequency Ablation Probe Placement

Under fluoroscopic guidance, anteroposterior (AP) and lateral images were obtained to localize each level and to confirm radiofrequency ablation (heater) probe position within the vertebral body, treating from the sacrum upward through the low thoracic spine — S1 through T12 — using the Stryker OptaBlate® system.

Anteroposterior (AP) fluoroscopic image showing Stryker OptaBlate heater probes positioned within the L5 and S1 vertebral bodies during basivertebral nerve ablation.
AP view

Anteroposterior (AP) view

L5 and S1 vertebral bodies

Anteroposterior (AP) image demonstrating fluoroscopic localization and positioning of the Stryker OptaBlate heater probes within the L5 and S1 vertebral bodies.

Lateral fluoroscopic image confirming the depth of the Stryker OptaBlate heater probes within the L5 and S1 vertebral bodies during basivertebral nerve ablation.
Lateral view

Lateral view

L5 and S1 vertebral bodies

Lateral image of the same L5 and S1 levels, confirming the depth of the Stryker OptaBlate heater probes within the vertebral bodies.

Anteroposterior (AP) fluoroscopic image showing Stryker OptaBlate heater probes positioned within the S1 and L4 vertebral bodies during basivertebral nerve ablation.
AP view

Anteroposterior (AP) view

S1 and L4 vertebral bodies

Anteroposterior (AP) image demonstrating the Stryker OptaBlate heater probes positioned within the S1 and L4 vertebral bodies.

Anteroposterior (AP) fluoroscopic image showing a Stryker OptaBlate heater probe positioned within the L3 vertebral body during basivertebral nerve ablation.
AP view

Anteroposterior (AP) view

L3 vertebral body

Anteroposterior (AP) image demonstrating the Stryker OptaBlate heater probe positioned within the L3 vertebral body.

Anteroposterior (AP) fluoroscopic image showing Stryker OptaBlate heater probes positioned within the L1 and L2 vertebral bodies during basivertebral nerve ablation.
AP view

Anteroposterior (AP) view

L1 and L2 vertebral bodies

Anteroposterior (AP) image demonstrating the Stryker OptaBlate heater probes positioned within the L1 and L2 vertebral bodies.

Lateral fluoroscopic image confirming the depth of the Stryker OptaBlate heater probes within the L1 and L2 vertebral bodies during basivertebral nerve ablation.
Lateral view

Lateral view

L1 and L2 vertebral bodies

Lateral image of the same L1 and L2 levels, confirming the depth of the Stryker OptaBlate heater probes within the vertebral bodies.

Lateral fluoroscopic image confirming the depth of the Stryker OptaBlate heater probes within the T12 and L3 vertebral bodies during basivertebral nerve ablation.
Lateral view

Lateral view

T12 and L3 vertebral bodies

Lateral image confirming the depth of the Stryker OptaBlate heater probes within the T12 and L3 vertebral bodies.

Anteroposterior (AP) fluoroscopic image showing a Stryker OptaBlate heater probe positioned within the T12 vertebral body during basivertebral nerve ablation.
AP view

Anteroposterior (AP) view

T12 vertebral body

Anteroposterior (AP) image demonstrating final positioning of the Stryker OptaBlate heater probe within the T12 vertebral body.

Follow-Up

The Clinical Course

Improvement following BVNA is frequently progressive; early symptoms are not the final outcome.

Early Recovery

At the one-week postoperative follow-up, the patient reported approximately 20% improvement in her previously described axial low back pain. Recovery was appropriate, and no procedure-related complications were identified.

She was counseled that improvement following Basivertebral Nerve Ablation is frequently progressive over the weeks following treatment.

Progressive Recovery

At the one-month follow-up, the patient reported approximately 40% improvement in her chronic axial low back pain, with steadily improving activity tolerance.

Long-Term Outcome

By approximately two months following the procedure, the patient reported an estimated 60% reduction in the chronic axial low back pain that had previously limited her quality of life. She described meaningful improvement in standing tolerance, walking tolerance, and routine daily activities.

Most importantly, she was able to resume community volunteer activities that had become increasingly difficult because of her chronic vertebrogenic pain, including volunteering with local animal rescue organizations and participating in community service activities that had previously brought significant purpose and enjoyment to her life. She described these improvements as restoring an important part of her independence and quality of life.

Outcome Summary

At a Glance

≈60%

reduction in chronic axial low back pain by ~2 months

Patient

78-year-old female

Diagnosis

Chronic vertebrogenic low back pain

Prior treatment

Extensive unsuccessful conservative care

Procedure

Multilevel BVNA (T12–S1), Stryker OptaBlate® system

One week / one month

≈20% → ≈40% improvement

Two months

≈60% improvement · returned to community volunteer work

Clinical Pearl

Patients often describe successful treatment in terms of the activities they regain rather than the amount of pain they lose. For many individuals with vertebrogenic pain, meaningful improvement is measured by returning to family responsibilities, hobbies, volunteer work, and community participation. Careful patient selection remains fundamental to identifying those most likely to benefit from Basivertebral Nerve Ablation.

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